Product ID:OCTICAIR OTIC SUSPENSION (NON-BUFFERED)
MSDS Date:09/07/1994
FSC:6505
NIIN:01-043-0230
Status Code:A
MSDS Number: CJTXL

BAUSCH & LOMB PHARMACEUTICALS, INC.

8500 HIDDEN RIVER PARKWAY
TAMPA, FL 33637
US

Emergency Phone: 800-227-1427

Info Phone: 800-323-0000

Preparer: THOMAS JENNINGS EHS CHEM

Cage: 0B6V3

TENNESSEE WHOLESALE DRUG CO ING

NASHVILLE, TN 37228-1804 US

Telephone: 615-244-8110

Cage: 0A423

HYDROCORTISONE

CAS: 50-23-7

NEOMYCIN SULFATE

CAS: 1404-04-2

POLYMYXIN B SULFATE

CAS: 1404-26-8

RTECS: TR1050000

CETYL ALCOHOL

CAS: 36653-82-4

RTECS: MM0225000

POLYOXYL 40 STEARATE

CAS: 9004-99-3

RTECS: MD0907300

POLYSORBATE 80

CAS: 9005-65-6

RTECS: WG2932500

THIMEROSAL

CAS: 54-64-8

RTECS: OV8400000

OSHA PEL 0.01 MG/CUM

ACGIH TLV: 0.01 MG/CUM

PURIFIED WATER

CAS: 7732-18-5

RTECS: ZC0110000

PROPYLENE GLYCOL

CAS: 57-55-6

RTECS: TY2000000

Routes of Entry: Inhalation:NO Skin:NO Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:CHRONIC EFFECTS: HYPERSENSITIZATION IS
POSSIBLE IN SOME INDIVIDUALS. LONG TERM USE MAY CAUSE OTOTOXICITY.
TARGET ORGANS: KIDNEY, SKIN, AND BRAIN. ACUTE: EYE: REDNESS,
SWELLING AND ITCHING OF THE EYE. SKIN: RASH, SWELLING, AND ITCHING
DUE TO HYPERSENSITIVITY. INGEST: MAY CAUSE ALLERGIC REACTION AND
COULD RESULT IN GASTROINTESTINAL IRRITATION. LARGE DOSE MAY INDUCE
KIDNEY INJURY. INHALE: NOT LIKELY.
Explanation of Carcinogenicity:NONE LISTED.
Medical Cond Aggravated by Exposure:HYPERSENSITIVITY TO NEOMYCIN
SULFATE, POLYMYXIN B SULFATE, HYDROCORTISONE OR ANY OF THE
COMPONENTS OF THE PRODUCT. ANAPHYLACTIC CROSS-REACTIONS MAY OCCUR.

First Aid:EYES: RINSE IMMEDIATELY WITH COPIUS AMOUNTS OF WATER FOR AT
LEAST 20 MINUTES. CONTACT A PHYSICIAN. SKIN: REMOVE ALL
CONTAMINATED CLOTHING AND WASH SKIN WITH COPIOUS AMOUNTS OF WATER
FOR AT LEAST 20 MI NUTES. CONTACT PHYSICAIN IF SKIN BECOMES
IRRITATED. INHALATION: REMOVE PERSON TO FRESH AIR, AND IF BREATHING
STOPS, USE ARTIFICIAL RESPIRATION. CONTAACT PHYSICIAN. NOTE TO
PHYSICIANS: HYDROCORTISONE A PPEARS IN THE MILK OF NURSING MOTHERS
WHEN ORALLY ADMINISTERED, SO CAUTION SHOULD BE EXERCISED WHEN
PRESCRIBINT OCTICAIR OTIC SUSPENSION.

Flash Point:NE
Extinguishing Media:DRY CHEMICAL, CARBON DIOXIDE, HALON, WATER SPRAY OR
FOG, AND FOAM.
Fire Fighting Procedures:WEAR SELF-CONTAINED BREATHING APPARATUS AND
PROTECTIVE CLOTHING. USE WATER SPRAY TO KEEP FIRE-EXPOSED
CONTAINERS COOL.
Unusual Fire/Explosion Hazard:EMITS TOXIC FUMES; MERCURY VAPORS(HG),
SULFUR OXIDES(SOX), NITROGEN OXIDES(NOX), SODIUM OXIDES(NA0).

Spill Release Procedures:USE PERSONAL PROTECTIVE EQUPMENT. CONTAIN THE
SPILL TO PREVENT FRAINAGE INTO SEWERS, DRAINS OR STREAMS. USE
ABSORBENT MATERIAL TO SOLIDIFY THE SPILL. SHOVEL OR SCOOP UP
SOLIDIFIED WASTE. DISPOSE OF MA TERIAL ACCORDING TO FEDERAL, STATE
AND LOCACAL REGULATIONS.

Handling and Storage Precautions:USE CAUTION TO PREVENT PUNCTURING
CONTAINERS. NO SPECIAL PROTECTIVE EQUIPMENT OR PROCEDURES ARE
REQUIRED IN THE HOME ENVIRONMENT. STORE PRODUCT UPRIGHT IN ORIGINAL
CONTAINERS WITH THE CAP TIGHTLY CLOS ED AT A CONTROLLED ROOM
TEMPERTURE 15-30 C(59-86F).
Other Precautions:HYDROCORTISONE APPEARS IN THE MILK OF NURSING MOTHERS
WHEN ORALLY ADMINISTERED, SO CAUTION SHOULD BE EXERCISED WHEN
PRESCRIBINT OCTICAIR OTIC SUSPENSION.

Respiratory Protection:(29 CFR 1910.134) NIOSH APPROVED RESPIRATOR
RECOMMENDED FOR RAW MATERIAL HANDLING. WARNING: NO NOT USE AIR
PURIFYING RESPIRATORS IN OXYGEN DEPLETED ENVIRONMENTS. UNLESS
VAPORS EXCEED THOSE STATED IN S ECTION 2 NO RESPORATORY PROTECTION
IS REQUIRED FOR HANDLING PRODUCT.
Ventilation:RECOMMEDED. REQUIRED IF VAPOR CONCENTRATION EXCEEDS THAT IN
SECTION 2. SEE ENGINEERING CONTROLS.
Protective Gloves:THICK IMPERMEABLE
Eye Protection:(29CFR1910.133) RECOMMEND GOGGLES OR CHEMICAL SAFETY
GLASSES.
Other Protective Equipment:THICK IMPERMEABLE PROTECTIVE CLOTHING.
Supplemental Safety and Health

HCC:T4
Boiling Pt:B.P. Text:NE
Vapor Pres:NE
Vapor Density:NE
Spec Gravity:1.
Viscosity:NE
Evaporation Rate & Reference:NE
Solubility in Water:MISCIBLE
Appearance and Odor:WHITE TO OFF-WHITE, FLOWING SUSPENSION
Percent Volatiles by Volume:<1

Stability Indicator/Materials to Avoid:YES
THIS PRODUCT HAS THE SAME INCOMPATIBILITIES AS WATER E.G. STRONG ACIDS,
BASES, ALKALI METALS, ALKALI HYDRIDES.
Stability Condition to Avoid:EXTREME HEAT OR COLD.
Hazardous Decomposition Products:MERCURY VAPORS (HG), TOXIC FUMES.
Conditions to Avoid Polymerization:SHOULD NOT POLYMERIZE.

Waste Disposal Methods:DISPOSE OF MATERIAL ACCORDING TO FEDERAL, STATE,
AMD LOCAL REGULATIONS. THE METHOD TYPICALLY USED IS INCINERATION OR
RECLAMATION.

Toxicological Information:HYDROCORTISONE: MAY CAUSE IRRITATION TO EYES,
SKIN AND RESPIRATORY TRACT. PROLONGED CONTACT CAN CAUSE
HYPERSENSITIVITY IN SOME INDIVIDUALS. THIMEROSAL: MAY CAUSE
IRRITATION TO MUCOUS MEMBRANES OF LUNG S AND EYES. SENSITIZATION
DERMATITIS MAY OCCUR IN PERSONS PREVIOUSLY EXPOSED.

Ecological:MERCURY COMPOUNDS SHOW AN INCREASED BIOLOGICAL CONCENTRATION
WHEN MOVING UP THE FOOD CHAIN. THIS MATERIAL DOES NOT DEGRADE OVER
TIME AND THEREFORE BUILDS UP WITHIN THE ENVIRONMENT.

Transport Information:DOT: DIVISION 6.1, PACKING GROUP III.

SARA Title III Information:THIMEROSAL IS A REPORTABLE SUBSTANCE UNDER
SARA SECTION 313 OF TOXIC RELEASE REPORTING. REPORTABLE QUANTITY IS
ONE POUND OR 0.454 KG OF MERCURY.

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.